Top 10 protein brands on Amazon (estimated revenue)

Ranked by estimated monthly revenue from Amazon's Protein Best Sellers top 100. Updated October 15, 2026.

Ensure is the top-selling protein brand on Amazon by estimated revenue, at about $2.5M/mo from 7 products in the Protein Best Sellers top 100. That is about the same as #2 Orgain (~$2.4M/mo). The list is fragmented: the top 3 brands take about 22% of its estimated sales and the top 10 about 51%, spread across 56 brands in total. The median list price in this top 100 is $34.99. All figures are modeled estimates, not Amazon data.

#BrandEst. revenue/moShare of listEst. units/moProductsBest rank
1Ensure8% share · best #3$2.5M8%77.2K7#3
2Orgain8% share · best #2$2.4M8%80.2K6#2
3Isopure6% share · best #14$1.9M6%35.3K3#14
4Optimum Nutrition5% share · best #1$1.7M5%36K2#1
5Dymatize4% share · best #4$1.4M4%39.5K3#4
6Transparent Labs4% share · best #5$1.4M4%21.6K1#5
7NAKED4% share · best #6$1.3M4%20.8K3#6
8Nutricost4% share · best #25$1.2M4%16.4K2#25
9Muscle Milk4% share · best #11$1.1M4%45.5K4#11
10Ascent3% share · best #22$1M3%11.5K1#22
Estimates, not official Amazon data. Rankings and revenue are modeled from public Amazon Best Sellers lists and list prices (units × price, before returns, discounts and fees; not profit) and may differ from real sales. How it works.

The top 10, brand by brand

1. Ensure

~$2.5M/mo est. revenue (8% of this list) and ~77.2K units/mo from 7 products; best position #3. Its highest-ranked product here is Ensure Max Protein Milk Chocolate Shake, 30g High Protein, 12 Pack | 30g… at #3. Overall it ranks #52 of 867 brands.

2. Orgain

~$2.4M/mo est. revenue (8% of this list) and ~80.2K units/mo from 6 products; best position #2. Its highest-ranked product here is Orgain Organic Vegan 21g Protein Powder, Vanilla Bean, 2.03 lb | Plant based… at #2. Overall it ranks #18 of 867 brands.

3. Isopure

~$1.9M/mo est. revenue (6% of this list) and ~35.3K units/mo from 3 products; best position #14. Its highest-ranked product here is Isopure Zero Carb Whey Isolate Protein Powder, Creamy Vanilla 3 LB | 25g… at #14. Overall it ranks #54 of 867 brands.

4. Optimum Nutrition

~$1.7M/mo est. revenue (5% of this list) and ~36K units/mo from 2 products; best position #1. Its highest-ranked product here is Optimum Nutrition Gold Standard Whey Protein Powder, Vanilla Ice Cream, 2LB… at #1. Overall it ranks #13 of 867 brands.

5. Dymatize

~$1.4M/mo est. revenue (4% of this list) and ~39.5K units/mo from 3 products; best position #4. Its highest-ranked product here is Dymatize ISO100 Protein Powder, 100% Whey Isolate, Gourmet Vanilla | 25g… at #4. Overall it ranks #55 of 867 brands.

6. Transparent Labs

~$1.4M/mo est. revenue (4% of this list) and ~21.6K units/mo from 1 product; best position #5. Its highest-ranked product here is Transparent Labs Grass-Fed Whey Protein - 30 Servings, French Vanilla… at #5. Overall it ranks #33 of 867 brands.

7. NAKED

~$1.3M/mo est. revenue (4% of this list) and ~20.8K units/mo from 3 products; best position #6. Its highest-ranked product here is NAKED Whey 2LB 100% Grass Fed Whey Protein Powder - Only 1 Ingredient… at #6. Overall it ranks #30 of 867 brands.

8. Nutricost

~$1.2M/mo est. revenue (4% of this list) and ~16.4K units/mo from 2 products; best position #25. Its highest-ranked product here is Nutricost Whey Protein Concentrate Powder (Unflavored) 2LBS, Gluten Free… at #25. Overall it ranks #2 of 867 brands.

9. Muscle Milk

~$1.1M/mo est. revenue (4% of this list) and ~45.5K units/mo from 4 products; best position #11. Its highest-ranked product here is Muscle Milk Pro Liquid High Protein Shake, Chocolate, 11 Fl Oz (Pack of 12)… at #11. Overall it ranks #56 of 867 brands.

10. Ascent

~$1M/mo est. revenue (3% of this list) and ~11.5K units/mo from 1 product; best position #22. Its highest-ranked product here is Ascent 100% Whey, Native Whey Protein Blend - Clean Post Workout Recovery… at #22. Overall it ranks #110 of 867 brands.

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