Best-selling digestive supplements brands on Amazon

By estimated revenue, Garden of Life is the best-selling digestive supplements brand on Amazon right now, at roughly $4M/mo from 6 products in the Digestive Supplements Best Sellers top 100 (best position #2). By estimated units, Physician's CHOICE sells the most, about 187K a month, usually at a lower price per unit. These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.

On October 15, 2026 the #1 product in Amazon's Digestive Supplements Best Sellers list was Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive… from Physician's CHOICE, with an estimated 108K units and ~$1.9M in revenue per month. Ranks change hourly, so check Amazon for the live list.

54 distinct brands have at least one product in the Digestive Supplements top 100. The 10 biggest by estimated revenue account for about 60% of the list's estimated sales, and the top 3 for about 26%.

We estimate the top 100 digestive supplements products together bring in about $42.8M a month at list price, before returns, discounts and fees. Treat it as an order-of-magnitude figure. These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.

We read the public Amazon Best Sellers list daily, match each product to its brand, estimate monthly units from Amazon's “bought in past month” badges and sales-rank curves, and multiply by list price. Full details are on the methodology page.