Best-selling weight loss supplements brands on Amazon

63 brands have products in the Amazon Best Sellers top 100 for Weight Loss Supplements. Ordered by how strongly each brand ranks in this list (higher positions and more products count more). List as of October 15, 2026.

Est. revenue/mo, top 100$32.7M
Brands in top 10063
Category leaderMetamucil~$2M/mo est.
#1 productSerene Herbs$3M/mo est.
#BrandBest rankProductsEst. units/moEst. revenue/moOverall score
1MetamucilBest #2 · 6 products#2684.2K$2M59.8
2VELOMIXBest #6 · 4 products#6437.8K$569K47.2
3BenefiberBest #7 · 4 products#7461.8K$1.3M52.8
4BlenderBottleBest #17 · 4 products#17429.3K$452K46.4
5VOLTRXBest #26 · 3 products#26314.4K$303K40.9
6OllyBest #15 · 2 products#15219.4K$332K66.3
7DiurexBest #35 · 2 products#35283.1K$808K52.1
8LemmeBest #39 · 3 products#39341.6K$1.6M59.6
9Serene HerbsBest #1 · 1 product#1175.2K$3M51.5
10Amazon BasicsBest #3 · 1 product#3154.1K$527K64.0
11MiraLAXBest #4 · 1 product#4127.1K$432K45.2
12nbpureBest #5 · 1 product#5131.7K$885K45.0
13VitamaticBest #32 · 2 products#32213K$209K68.5
14NutricostBest #51 · 2 products#51255.5K$908K97.0
15FOODOLOGYBest #8 · 1 product#8120.2K$444K49.3
16Global HealingBest #9 · 1 product#9123.8K$714K52.2
17Tomorrow'sBest #10 · 1 product#10116.7K$416K44.5
18Dr. TobiasBest #11 · 1 product#11119.5K$389K46.5
19YETIBest #13 · 1 product#13112.5K$312K40.4
20alliBest #14 · 1 product#1415.4K$352K46.2
21BelliBest #19 · 1 product#19111.7K$233K43.0
22THORNEBest #41 · 2 products#41226.7K$946K77.9
23Pure for MenBest #21 · 1 product#21110.3K$308K40.1
24Physician's CHOICEBest #24 · 1 product#2419.7K$232K62.2
25MilaBest #25 · 1 product#25113.2K$263K43.5
26BioteBest #27 · 1 product#27112K$696K41.7
27HorbäachBest #28 · 1 product#2816.9K$88K79.4
28Nature MadeBest #29 · 1 product#2919.2K$147K79.9
29SupergutBest #30 · 1 product#3018.8K$263K40.7
30VINATURABest #33 · 1 product#33111K$210K46.4
31GOBIOTIXBest #34 · 1 product#3418.4K$243K40.6
32Lil CrittersBest #36 · 1 product#3618K$82K41.6
33InnoSuppsBest #38 · 1 product#38110.3K$400K40.7
34JSHealthBest #42 · 1 product#4219.6K$374K41.0
35NaturaLife LabsBest #44 · 1 product#44151.4K$872K52.1
36NutramaxBest #46 · 1 product#4619K$596K47.8
37VitafusionBest #48 · 1 product#4816.9K$104K58.5
38DR VITAMIN SOLUTIONSBest #50 · 1 product#5013.2K$57K38.6
39ResciencyBest #52 · 1 product#5218.1K$152K38.2
40C4Best #54 · 1 product#5415.4K$138K50.4
41SmartyPantsBest #72 · 2 products#72210.3K$224K52.6
42CitrucelBest #59 · 2 products#59210.9K$294K39.5
43ALPHA LIONBest #58 · 1 product#5814.2K$229K48.6
44HUMBest #60 · 1 product#6016.1K$184K46.3
45Renew LifeBest #62 · 1 product#6217.4K$178K48.1
46BoochBodBest #64 · 1 product#6416K$167K36.7
47BellaBest #65 · 1 product#6517.1K$198K39.3
48Bloom NutritionBest #68 · 1 product#6815.7K$113K51.3
49Night ShredBest #69 · 1 product#6913.7K$184K35.3
50PendulumBest #71 · 1 product#7115.4K$346K42.1
51Jacked FactoryBest #75 · 1 product#75113.2K$329K52.9
52Sculpt NationBest #78 · 1 product#7813.4K$166K39.2
53Nature's TruthBest #79 · 1 product#7916.5K$65K63.1
54ForestLeafBest #83 · 1 product#83119.5K$584K53.4
55Member's MarkBest #84 · 1 product#8415.2K$84K37.2
56Zarbee'sBest #87 · 1 product#8715.1K$78K49.8
57Healthy OriginsBest #88 · 1 product#8814.9K$94K50.2
58AKKABest #89 · 1 product#8916.1K$391K36.2
59NatureBellBest #90 · 1 product#9014.3K$86K65.1
60JoySpringBest #91 · 1 product#9115.9K$207K45.1
61AnimalBest #93 · 1 product#9313K$140K55.0
62OmegaXLBest #94 · 1 product#9413K$285K36.1
63BRAGGBest #96 · 1 product#9615.7K$199K46.4

Top 10 Weight Loss Supplements products

#ProductBrandEst. revenue/mo
1Serene Herbs Soursop Bitters, Herbal Liquid with Soursop Leaf, 16 fl oz
Serene Herbs
Serene Herbs$3M
2Metamucil 4-in-1 Psyllium Husk GLP-1 Friendly Fiber Supplement, Sugar-Free, 72 teaspoons…
Metamucil
Metamucil$778K
3Amazon Basics Fiber 4g Gummy - Digestive Health, Supports Regularity, Orange, Lemon &…
Amazon Basics
Amazon Basics$527K
4MiraFIBER Gummies, from The Makers of MiraLAX, Vegan Formula, 8g Per Serving, Gut Health…
MiraLAX
MiraLAX$432K
5nbpure MagO7 - Natural Colon Cleanse & Detox | Occasional Constipation Relief, Stool…
nbpure
nbpure$885K
6VELOMIX 2 Pack 28oz Protein Shaker Bottle for Protein Mixes, Black/Transpar | 2x Wire…
VELOMIX
VELOMIX$279K
7Benefiber Prebiotic Fiber Supplement Powder, Unflavored, 250 Teaspoons | Plant-based…
Benefiber
Benefiber$871K
8FOODOLOGY Coleology Cutting Jelly, Pomegranate Flavor, 10 Sticks | Dietary Fiber…
FOODOLOGY
FOODOLOGY$444K
9Global Healing Oxy-Powder Colon Cleanse, Magnesium Oxide, 60 Capsules | Gentle overnight…
Global Healing
Global Healing$714K
10Tomorrow's Nutrition, Fiber, GLP-1 Friendly, Made with Sunfiber, Unflavored | Prebiotic…
Tomorrow's
Tomorrow's$416K

As an Amazon Associate, SuppRanked earns from qualifying purchases.

Estimates, not official Amazon data. Rankings and revenue are modeled from public Amazon Best Sellers lists and list prices (units × price, before returns, discounts and fees; not profit) and may differ from real sales. How it works.

Explore more

Top 10 Weight Loss Supplements brands by revenue

Serene Herbs, Metamucil, Lemme and seven more, with each brand's estimated revenue share.

See the top 10 →

Head-to-head comparisons

Related categories

Weight Loss Supplements brands on Amazon: FAQ

What is the best-selling weight loss supplements brand on Amazon?

By estimated revenue, Serene Herbs is the best-selling weight loss supplements brand on Amazon right now, at roughly $3M/mo from 1 product in the Weight Loss Supplements Best Sellers top 100 (best position #1). By estimated units, Metamucil sells the most, about 84.2K a month, usually at a lower price per unit. These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.

What is the #1 best-selling weight loss supplements product on Amazon?

On October 15, 2026 the #1 product in Amazon's Weight Loss Supplements Best Sellers list was Serene Herbs Soursop Bitters, Herbal Liquid with Soursop Leaf, 16 fl oz from Serene Herbs, with an estimated 75.2K units and ~$3M in revenue per month. Ranks change hourly, so check Amazon for the live list.

How many weight loss supplements brands are in Amazon's top 100?

63 distinct brands have at least one product in the Weight Loss Supplements top 100. The 10 biggest by estimated revenue account for about 48% of the list's estimated sales, and the top 3 for about 24%.

How much do the top weight loss supplements products sell on Amazon?

We estimate the top 100 weight loss supplements products together bring in about $32.7M a month at list price, before returns, discounts and fees. Treat it as an order-of-magnitude figure. These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.

How are these rankings calculated?

We read the public Amazon Best Sellers list daily, match each product to its brand, estimate monthly units from Amazon's “bought in past month” badges and sales-rank curves, and multiply by list price. Full details are on the methodology page.

SponsorYour brand here

Reach the supplement founders, operators and investors who check where they rank. $499/mo, 20/20 spots open.

Advertise on SuppRanked →

Other categories

Vitamins, Minerals & SupplementsDiet & Sports NutritionSports NutritionHerbal SupplementsVitaminsAmino AcidsAntioxidantsVitamin BEssential Fatty AcidsMineralsProteinCreatineDigestive SupplementsCollagenWeight GainersWeight LossDiet Kits & SystemsProbioticsGlandular ExtractsColloidal GoldEndurance & EnergyMagnesiumEnzymesAcidophilus7-KetoProtein BlendsPolyphenolsBlended Vitamin & Mineral SupplementsEnergy ShotsWhey ProteinMultivitaminsFruit ExtractsColloidal MineralsPrenatal VitaminsPlant ProteinKava KavaFrench Maritime Pine Bark ExtractChondroitin & GlucosamineB7 (Biotin)All 229 categories →