Top 10 weight loss supplements brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Weight Loss Supplements Best Sellers top 100. Updated October 15, 2026.
Serene Herbs is the top-selling weight loss supplements brand on Amazon by estimated revenue, at about $3M/mo from 1 product in the Weight Loss Supplements Best Sellers top 100. That is about 51% more than #2 Metamucil (~$2M/mo). The list is fragmented: the top 3 brands take about 24% of its estimated sales and the top 10 about 48%, spread across 63 brands in total. About 19% of the products are gummies. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Serene Herbs11% share · best #1 | $3M |
| 2 | Metamucil8% share · best #2 | $2M |
| 3 | Lemme6% share · best #39 | $1.5M |
| 4 | Benefiber5% share · best #7 | $1.3M |
| 5 | THORNE3% share · best #41 | $913K |
| 6 | Nutricost3% share · best #51 | $861K |
| 7 | nbpure3% share · best #5 | $838K |
| 8 | NaturaLife Labs3% share · best #44 | $826K |
| 9 | Diurex3% share · best #35 | $765K |
| 10 | Global Healing3% share · best #9 | $676K |
The top 10, brand by brand
1. Serene Herbs
~$3M/mo est. revenue (11% of this list) and ~75.2K units/mo from 1 product; best position #1. Its highest-ranked product here is Serene Herbs Soursop Bitters, Herbal Liquid with Soursop Leaf, 16 fl oz at #1. Overall it ranks #137 of 3,479 brands.
2. Metamucil
~$2M/mo est. revenue (8% of this list) and ~84.2K units/mo from 6 products; best position #2. Its highest-ranked product here is Metamucil 4-in-1 Psyllium Husk GLP-1 Friendly Fiber Supplement, Sugar-Free, 72… at #2. Overall it ranks #45 of 3,479 brands.
3. Lemme
~$1.5M/mo est. revenue (6% of this list) and ~39.9K units/mo from 3 products; best position #39. Its highest-ranked product here is Lemme Burn Belly Fat & Metabolism Gummies for Women, 30-Day Supply | Clinically… at #39. Overall it ranks #46 of 3,479 brands.
4. Benefiber
~$1.3M/mo est. revenue (5% of this list) and ~61.8K units/mo from 4 products; best position #7. Its highest-ranked product here is Benefiber Prebiotic Fiber Supplement Powder, Unflavored, 250 Teaspoons… at #7. Overall it ranks #113 of 3,479 brands.
5. THORNE
~$913K/mo est. revenue (3% of this list) and ~25.6K units/mo from 2 products; best position #41. Its highest-ranked product here is THORNE FiberMend, Prebiotic Fiber Powder with Antioxidants, 30 Servings… at #41. Overall it ranks #8 of 3,479 brands.
6. Nutricost
~$861K/mo est. revenue (3% of this list) and ~52.6K units/mo from 2 products; best position #51. Its highest-ranked product here is Nutricost Acetyl L-Carnitine (ALCAR) 500mg, 180 Capsules | GMO-Free and Gluten… at #51. Overall it ranks #2 of 3,479 brands.
7. nbpure
~$838K/mo est. revenue (3% of this list) and ~30K units/mo from 1 product; best position #5. Its highest-ranked product here is nbpure MagO7 - Natural Colon Cleanse & Detox | Occasional Constipation Relief… at #5. Overall it ranks #405 of 3,479 brands.
8. NaturaLife Labs
~$826K/mo est. revenue (3% of this list) and ~48.7K units/mo from 1 product; best position #44. Its highest-ranked product here is NaturaLife Labs Acetyl L-Carnitine (ALCAR) 1500 mg per Serving – 100 Capsules… at #44. Overall it ranks #126 of 3,479 brands.
9. Diurex
~$765K/mo est. revenue (3% of this list) and ~78.7K units/mo from 2 products; best position #35. Its highest-ranked product here is Diurex Ultra Re-Energizing Water Pills - Relieve Water Bloat - Feel Better &… at #35. Overall it ranks #127 of 3,479 brands.
10. Global Healing
~$676K/mo est. revenue (3% of this list) and ~22.6K units/mo from 1 product; best position #9. Its highest-ranked product here is Global Healing Oxy-Powder Colon Cleanse, Magnesium Oxide, 60 Capsules | Gentle… at #9. Overall it ranks #128 of 3,479 brands.
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Full Weight Loss Supplements ranking
All 63 brands in the list, ordered by rank strength, plus the top 10 products.
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