SuppRankedTop 10 probiotics brands on Amazon (estimated revenue)
Ranked by estimated monthly revenue from Amazon's Probiotics Best Sellers top 100. Updated October 15, 2026.
Physician's CHOICE is the top-selling probiotics brand on Amazon by estimated revenue, at about $3.3M/mo from 3 products in the Probiotics Best Sellers top 100. That is about the same as #2 Garden of Life (~$3.3M/mo). The list is fragmented: the top 3 brands take about 32% of its estimated sales and the top 10 about 65%, spread across 49 brands in total. The median list price in this top 100 is $25.99, and 11% of the products are gummies. All figures are modeled estimates, not Amazon data.
| # | Brand | Est. revenue/mo |
|---|---|---|
| 1 | Physician's CHOICE11% share · best #1 | $3.3M |
| 2 | Garden of Life11% share · best #2 | $3.3M |
| 3 | Align10% share · best #14 | $2.9M |
| 4 | Seed8% share · best #4 | $2.5M |
| 5 | Culturelle7% share · best #5 | $2.3M |
| 6 | Florastor6% share · best #7 | $1.7M |
| 7 | Lemme4% share · best #10 | $1.2M |
| 8 | ZBiotics3% share · best #8 | $909K |
| 9 | BIOMA3% share · best #16 | $808K |
| 10 | Microbiome Labs2% share · best #27 | $714K |
The top 10, brand by brand
1. Physician's CHOICE
~$3.3M/mo est. revenue (11% of this list) and ~167K units/mo from 3 products; best position #1. Its highest-ranked product here is Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics… at #1. Overall it ranks #22 of 867 brands.
2. Garden of Life
~$3.3M/mo est. revenue (11% of this list) and ~117K units/mo from 9 products; best position #2. Its highest-ranked product here is Garden of Life Dr. Formulated Once Daily Women's Probiotics, 50B CFU, 30ct | 50… at #2. Overall it ranks #9 of 867 brands.
3. Align
~$2.9M/mo est. revenue (10% of this list) and ~75.1K units/mo from 9 products; best position #14. Its highest-ranked product here is Align Probiotic, Pro Formula, Probiotics for Women and Men, Probiotics for… at #14. Overall it ranks #58 of 867 brands.
4. Seed
~$2.5M/mo est. revenue (8% of this list) and ~42.1K units/mo from 1 product; best position #4. Its highest-ranked product here is Seed DS-01 Daily Synbiotic - Adult Probiotic + Prebiotic - 30-Days with Jar… at #4. Overall it ranks #104 of 867 brands.
5. Culturelle
~$2.3M/mo est. revenue (7% of this list) and ~89.6K units/mo from 6 products; best position #5. Its highest-ranked product here is Culturelle Pro Strength Probiotics for Digestive Gut Health*, 12B CFU, 60ct… at #5. Overall it ranks #40 of 867 brands.
6. Florastor
~$1.7M/mo est. revenue (6% of this list) and ~32.1K units/mo from 2 products; best position #7. Its highest-ranked product here is Florastor Probiotic for Digestive and Immune Health, 100 Capsules | Probiotics… at #7. Overall it ranks #148 of 867 brands.
7. Lemme
~$1.2M/mo est. revenue (4% of this list) and ~39.6K units/mo from 2 products; best position #10. Its highest-ranked product here is Lemme Purr Vaginal Probiotic Gummies for Women, 30-Day Supply | Balanced pH… at #10. Overall it ranks #28 of 867 brands.
8. ZBiotics
~$909K/mo est. revenue (3% of this list) and ~25.2K units/mo from 1 product; best position #8. Its highest-ranked product here is ZBiotics Pre-Alcohol Probiotic — Drink Responsibly, for an Easier Tomorrow at #8. Overall it ranks #166 of 867 brands.
9. BIOMA
~$808K/mo est. revenue (3% of this list) and ~15.5K units/mo from 1 product; best position #16. Its highest-ranked product here is BIOMA Probiotics - Digestive Health Probiotic - Gut Support for Men & Women… at #16. Overall it ranks #220 of 867 brands.
10. Microbiome Labs
~$714K/mo est. revenue (2% of this list) and ~10.8K units/mo from 1 product; best position #27. Its highest-ranked product here is Microbiome Labs Mega SporeBiotic Daily Probiotic for Women + Men, 60 Ct at #27. Overall it ranks #285 of 867 brands.
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Full Probiotics ranking
All 49 brands in the list, ordered by rank strength, plus the top 10 products.
See all Probiotics brands →