SuppRankedBest-selling multi-enzymes brands on Amazon
53 brands have products in the Amazon Best Sellers top 100 for Multi-Enzymes. Ordered by how strongly each brand ranks in this list (higher positions and more products count more). List as of October 15, 2026.
Top 10 Multi-Enzymes products
| # | Product | Est. revenue/mo |
|---|---|---|
| 1 | Physician's CHOICE Digestive Enzymes for Bloating & Digestion - Fast-Acting 16 Enzyme… Physician's CHOICE | $1.3M |
| 2 | Physician's CHOICE Advanced Gut Health Bundle: 60 Billion Probiotics 30ct + Digestive… Physician's CHOICE | $1.3M |
| 3 | Enzymedica Digest Gold, Maximum Strength, ATPro Energy Support - 90 Caps | Digestive… Enzymedica | $1M |
| 4 | Now Foods Super Enzymes, 180 Capsules NOW Foods | $491K |
| 5 | Micro Ingredients Nattokinase 10,000 FU Per Serving, 240 Veggie Capsules | Natural Natto… Micro Ingredients | $517K |
| 6 | Pure Encapsulations Digestive Enzymes Ultra, 90 Capsules | Vegetarian Digestive Enzyme… Pure Encapsulations | $596K |
| 7 | American Health Super Papaya Enzyme Plus Chewable Tablets, 360 Count American Health | $216K |
| 8 | HUM Flatter Me Digestive Enzymes, Digestion & Bloating Support, 60 Count | 18 Digestive… HUM | $324K |
| 9 | FODZYME® Home Kit Digestive Enzymes for Gut Health, Relief for Bloating, Gas… FODZYME | $839K |
| 10 | Dr. Berg Gallbladder Formula Extra Strength - with Ox Bile Powder and Conjugated Bile… Dr. Berg | $389K |
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Top 10 Multi-Enzymes brands by revenue
Physician's CHOICE, Enzymedica, Pure Encapsulations and seven more, with each brand's estimated revenue share.
See the top 10 →Head-to-head comparisons
Multi-Enzymes brands on Amazon: FAQ
What is the best-selling multi-enzymes brand on Amazon?
By estimated revenue, Physician's CHOICE is the best-selling multi-enzymes brand on Amazon right now, at roughly $2.6M/mo from 2 products in the Multi-Enzymes Best Sellers top 100 (best position #1). These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.
What is the #1 best-selling multi-enzymes product on Amazon?
On October 15, 2026 the #1 product in Amazon's Multi-Enzymes Best Sellers list was Physician's CHOICE Digestive Enzymes for Bloating & Digestion - Fast-Acting 16 Enzyme Formula with… from Physician's CHOICE, with an estimated 67.3K units and ~$1.3M in revenue per month. Ranks change hourly, so check Amazon for the live list.
How many multi-enzymes brands are in Amazon's top 100?
53 distinct brands have at least one product in the Multi-Enzymes top 100. The 10 biggest by estimated revenue account for about 65% of the list's estimated sales, and the top 3 for about 40%.
How much do the top multi-enzymes products sell on Amazon?
We estimate the top 100 multi-enzymes products together bring in about $16.6M a month at list price, before returns, discounts and fees. Treat it as an order-of-magnitude figure. These are SuppRanked's modeled estimates from public Amazon Best Sellers ranks and list prices (October 15, 2026), not official Amazon sales data.
How are these rankings calculated?
We read the public Amazon Best Sellers list daily, match each product to its brand, estimate monthly units from Amazon's “bought in past month” badges and sales-rank curves, and multiply by list price. Full details are on the methodology page.
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